Photorhabdus luminescens Toxins as Therapeutic Agents: Difference between revisions

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<br>Introduce the topic of your paper.  What is your research question? What experiments have addressed your question?  Applications for medicine and/or environment?
<br>Introduce the topic of your paper.  What is your research question? What experiments have addressed your question?  Applications for medicine and/or environment?
<i>Photorhabdus luminescens<i> is a gram negative pathogenic bacteria that engages in a symbiotic relationship with nematodes. P. <i>luminescens<i> is the only known terrestrial bacteria that performs bioluminescent reactions. P. <i>luminescens<i> are a part of the photorhabdus genus of the <i>Enterobacteriaceae<i> family. There are three species of <i>Photorhabdus<i>,with two of them living in nematodes, and the third has been found in human wounds.  
<i>Photorhabdus luminescens<i> is a gram negative pathogenic bacteria that engages in a symbiotic relationship with nematodes. P. <i>luminescens<i> is the only known terrestrial bacteria that performs bioluminescent reactions. P. <i>luminescens<i> are a part of the photorhabdus genus of the <i>Enterobacteriaceae<i> family. There are three species of <i>Photorhabdus<i>,with two of them living in nematodes, and the third has been found in human wounds. P. <i>luminescens<i> is interesting as a microbe because it engages in symbiotic and pathogenic activities. In terms of symbiosis, P. <i>luminescens<i> lives in the gut of nematodes until the nematode infects a small insect like caterpillars. Once in the caterpillar, the nematode releases P. <i>luminescens<i>, where it releases a variety of toxins to kill the organism and provide nutrients for itself and for the nematode. These toxins are being looked at as potential therapeutic agents because of their efficacy as antimicrobial agents.
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Sample citations: <ref name=aa>[http://www.plosbiology.org/article/fetchObject.action?uri=info%3Adoi%2F10.1371%2Fjournal.pbio.1000005&representation=PDF Hodgkin, J. and Partridge, F.A. "<i>Caenorhabditis elegans</i> meets microsporidia: the nematode killers from Paris." 2008. PLoS Biology 6:2634-2637.]</ref>
Sample citations: <ref name=aa>[http://www.plosbiology.org/article/fetchObject.action?uri=info%3Adoi%2F10.1371%2Fjournal.pbio.1000005&representation=PDF Hodgkin, J. and Partridge, F.A. "<i>Caenorhabditis elegans</i> meets microsporidia: the nematode killers from Paris." 2008. PLoS Biology 6:2634-2637.]</ref>

Revision as of 02:30, 17 March 2021

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Electron micrograph of the Ebola Zaire virus. This was the first photo ever taken of the virus, on 10/13/1976. By Dr. F.A. Murphy, now at U.C. Davis, then at the CDC.


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Introduce the topic of your paper. What is your research question? What experiments have addressed your question? Applications for medicine and/or environment? Photorhabdus luminescens is a gram negative pathogenic bacteria that engages in a symbiotic relationship with nematodes. P. luminescens is the only known terrestrial bacteria that performs bioluminescent reactions. P. luminescens are a part of the photorhabdus genus of the Enterobacteriaceae family. There are three species of Photorhabdus,with two of them living in nematodes, and the third has been found in human wounds. P. luminescens is interesting as a microbe because it engages in symbiotic and pathogenic activities. In terms of symbiosis, P. luminescens lives in the gut of nematodes until the nematode infects a small insect like caterpillars. Once in the caterpillar, the nematode releases P. luminescens, where it releases a variety of toxins to kill the organism and provide nutrients for itself and for the nematode. These toxins are being looked at as potential therapeutic agents because of their efficacy as antimicrobial agents.
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Authored for BIOL 238 Microbiology, taught by Joan Slonczewski, 2021, Kenyon College.