Plasmodium falciparum: New Developments: Difference between revisions

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==Background==
==Background==
<i>Plasmodium falciparum</i> is a protozoan of the eukaryotic domain. It is widely known in today's world as one of the most common malarial parasites. This particular species causes malignant malaria, which leads to the most complications and mortality rates of all malaria-causing agents. It is estimated that between 300 million and 500 million people are afflicted with malaria annually (WHO). The majority of these incidences of malaria occur in sub-Saharan Africa and affect children under 5. According to the CDC, there are 156 species of <i>Plasmodium</i>, four of which are considered parasitic to humans. These include <i>P. falciparum, P. vivax, P. ovale and P. malaria</i>. Plasmodium falciparum has the highest rate of malarial infection among the four species <ref>[https://www.cdc.gov/dpdx/malaria/]</ref>. We know for a fact that <i>P. falciparum</i> is a malarial parasite that targets humans. What is relatively unknown, however, is the exact mechanism by which the protozoa are able to enter the cell and cause disease.
<i>Plasmodium falciparum</i> is a protozoan of the eukaryotic domain. It is widely known in today's world as one of the most common malarial parasites. This particular species causes malignant malaria, which leads to the most complications and mortality rates of all malaria-causing agents. It is estimated that between 300 million and 500 million people are afflicted with malaria annually (WHO). The majority of these incidences of malaria occur in sub-Saharan Africa and affect children under 5. According to the CDC, there are 156 species of <i>Plasmodium</i>, four of which are considered parasitic to humans. These include <i>P. falciparum, P. vivax, P. ovale and P. malaria</i>. <i>Plasmodium falciparum</i> has the highest rate of malarial infection among the four species <ref>[https://www.cdc.gov/dpdx/malaria/]</ref>. We know for a fact that <i>P. falciparum</i> is a malarial parasite that targets humans. What is relatively unknown, however, is the exact mechanism by which the protozoa are able to enter the cell and cause disease.
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Revision as of 14:44, 28 April 2017

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Section

Electron micrograph of Plasmodium falciparum. 2006.


By Charley Myers

Figure 2. Hemoglobin degradation pathway in P. falciparum. Francis et al 1997.
Figure 3. Nature Reviews. Life cycle of P. falciparum in both human host and mosquito vector.
Figure 4. Salleres et al 2004. “Infant burial no. 36, an inhumation burial, at the cemetery at Lugnano, in Taverna.”
Figure 5. Yang et al 2017. Immunofluorescence microscopy labeling SPECT and PLP1 proteins in Plasmodium falciparum (Pf).
Figure 6. Yang et al 2017. Measurements of P. falciparum presence in human liver cells. NF54 are wild type while PfPLP1 D2 are the PLP knockout strains of P. falciparum.

Introduction

Plasmodium falciparum is a protozoan of the eukaryotic domain. It is most widely known in today's world as one of the most common malarial parasites. This particular species causes malignant malaria, which leads to the most complications and mortality rates of any other malaria-causing agent. [1]


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Background

Plasmodium falciparum is a protozoan of the eukaryotic domain. It is widely known in today's world as one of the most common malarial parasites. This particular species causes malignant malaria, which leads to the most complications and mortality rates of all malaria-causing agents. It is estimated that between 300 million and 500 million people are afflicted with malaria annually (WHO). The majority of these incidences of malaria occur in sub-Saharan Africa and affect children under 5. According to the CDC, there are 156 species of Plasmodium, four of which are considered parasitic to humans. These include P. falciparum, P. vivax, P. ovale and P. malaria. Plasmodium falciparum has the highest rate of malarial infection among the four species [4]. We know for a fact that P. falciparum is a malarial parasite that targets humans. What is relatively unknown, however, is the exact mechanism by which the protozoa are able to enter the cell and cause disease.


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Include some current research, with at least one figure showing data.

Section 3

Include some current research, with at least one figure showing data.

Section 4

Conclusion

References



Authored for BIOL 238 Microbiology, taught by Joan Slonczewski, 2017, Kenyon College.