Salmonella enterica serovar Paratyphi: Difference between revisions
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==Treatment== | ==Treatment== | ||
==Prevention== | ==Prevention== | ||
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===Immunization=== | |||
==Host Immune Response== | ==Host Immune Response== | ||
When the body is infected by Salmonella Paratyphi, a humoral immune response is mounted. The response primarily takes place in the intestinal tract, since the gut is the first line of defense against enteric diseases [3]. Based on research performed with the Ty21a-vaccine, after the host was exposed to the oral vaccine, there was a predominance of IgA antibodies. As part of the immune response, it is believed that after the B cells arrive in the intestinal lining, they undergo isotype switching from IgM to IgA. This specific immunoglobulin isotype is produced to stimulate the destruction of Salmonella bacteria. Other research indicates that a cell-mediated response is also activated upon infection. [2] | When the body is infected by Salmonella Paratyphi, a humoral immune response is mounted. The response primarily takes place in the intestinal tract, since the gut is the first line of defense against enteric diseases [3]. Based on research performed with the Ty21a-vaccine, after the host was exposed to the oral vaccine, there was a predominance of IgA antibodies. As part of the immune response, it is believed that after the B cells arrive in the intestinal lining, they undergo isotype switching from IgM to IgA. This specific immunoglobulin isotype is produced to stimulate the destruction of Salmonella bacteria. Other research indicates that a cell-mediated response is also activated upon infection. [2] | ||
Revision as of 22:09, 15 July 2014
Etiology/Bacteriology
Pathogenesis
Clinical features
Diagnosis
Treatment
Prevention
Risk Avoidance
Immunization
Host Immune Response
When the body is infected by Salmonella Paratyphi, a humoral immune response is mounted. The response primarily takes place in the intestinal tract, since the gut is the first line of defense against enteric diseases [3]. Based on research performed with the Ty21a-vaccine, after the host was exposed to the oral vaccine, there was a predominance of IgA antibodies. As part of the immune response, it is believed that after the B cells arrive in the intestinal lining, they undergo isotype switching from IgM to IgA. This specific immunoglobulin isotype is produced to stimulate the destruction of Salmonella bacteria. Other research indicates that a cell-mediated response is also activated upon infection. [2]
References
References
Created by {insert your names here}, students of Tyrrell Conway at the University of Oklahoma.
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