Togaviridae: Difference between revisions
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==Genome Structure== | ==Genome Structure== | ||
The togavirus genome is non-segmented and contains a molecule of linear, positive-sense, single-stranded RNA. The complete genome is 9700-11800 nucleotides long. The 5'-terminus has a methylated nucleotide cap. (source: | The togavirus genome is non-segmented and contains a molecule of linear, positive-sense, single-stranded RNA. The complete genome is 9700-11800 nucleotides long. The 5'-terminus has a methylated nucleotide cap. (source: [http://phene.cpmc.columbia.edu/ICTVdB/00.073.htm ICTVdB]) | ||
==Virion Structure of a Togavirus== | ==Virion Structure of a Togavirus== | ||
Togavirus virions consist of an envelope and a nucleocapsid. | Togavirus virions consist of an envelope and a nucleocapsid. The virions are spheical to pleomorphic in shape, and about 70nm in diameter. Glycoprotein spikes evenly cover the surface of the virion. The genome is contained in the T=4 icosahedral capsid, which measures 40 nm in diameter. (sources: Garoff, [http://phene.cpmc.columbia.edu/ICTVdB/00.073.htm ICTVdB]) | ||
==Reproduction Cycle of a Togavirus in a Host Cell== | ==Reproduction Cycle of a Togavirus in a Host Cell== | ||
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==References== | ==References== | ||
Garoff, Henrik, Mathilda Sjöberg and R. Holland Cheng. "Budding of Alphaviruses." <u>Virus Research</u> 106.2 (2004): 103-116. | |||
[http://phene.cpmc.columbia.edu/ICTVdB/00.073.htm ICTVdB - The Universal Virus Database, version 4. http://www.ncbi.nlm.nih.gov/ICTVdb/ICTVdB/] | [http://phene.cpmc.columbia.edu/ICTVdB/00.073.htm ICTVdB - The Universal Virus Database, version 4. http://www.ncbi.nlm.nih.gov/ICTVdb/ICTVdB/] | ||
Revision as of 18:15, 20 June 2006
Baltimore Classification
Higher order taxa
Viruses; ssRNA positive-strand viruses, no DNA stage; Togaviridae
Genera
Alphavirus, Rubivirus
Description and Significance
Genome Structure
The togavirus genome is non-segmented and contains a molecule of linear, positive-sense, single-stranded RNA. The complete genome is 9700-11800 nucleotides long. The 5'-terminus has a methylated nucleotide cap. (source: ICTVdB)
Virion Structure of a Togavirus
Togavirus virions consist of an envelope and a nucleocapsid. The virions are spheical to pleomorphic in shape, and about 70nm in diameter. Glycoprotein spikes evenly cover the surface of the virion. The genome is contained in the T=4 icosahedral capsid, which measures 40 nm in diameter. (sources: Garoff, ICTVdB)
Reproduction Cycle of a Togavirus in a Host Cell
Viral Ecology & Pathology
References
Garoff, Henrik, Mathilda Sjöberg and R. Holland Cheng. "Budding of Alphaviruses." Virus Research 106.2 (2004): 103-116.
ICTVdB - The Universal Virus Database, version 4. http://www.ncbi.nlm.nih.gov/ICTVdb/ICTVdB/
