User:S4415589

Name: Jovin Choo Jia Ying
Bench: E
Date: 31 August 2016
Porphyromonas gingivalis

Classification

Higher order taxa

Bacteria – Bacteria – Bacteroidetes – Bacteroide – Bacteroidales – Porphyromonadaceae – Porphyromonas

Species

Species name: Porphyromonas gingivalis
Type strains: 381, 2561, ATCC 33277, BCRC 14417, CCRC 14417, CCUG 25893, CCUG 25928, CIP 103683, Coykendall 2561, DSM 20709, JCM 12257, KCTC 5121, KDI, NCTC 11834, Slots 2561, SU63, W50, W83
(consult LPSN http://www.bacterio.net/index.html for this information)

Description and significance

Give a general description of the species (e.g. where/when was it first discovered, where is it commonly found, has it been cultured, functional role, type of bacterium [Gram+/-], morphology, etc.) and explain why it is important to study this microorganism. Examples of citations ^[1], ^[2]

Porphyromonas gingivalis is found in 86% of subgingival plaque samples from patients suffering from chronic periodontitis. P. gingivalis is a non-motile, asaccharolytic, obligate anaerobe, gram negative, rod shaped bacterium. It is known to form black-pigmented colonies after being culture for 6-10 days on blood agar due to accumulation of heme. It requires iron for its growth. P. gingivalis was previously named Bacteroides gingivalis before reclassification into a new genus. It is a secondary colonizer of dental plaque which adheres to primary colonizer such as Streptococcus gordonii and P. intermedia.

As P. gingivalis is a prime etiological agent that causes severe forms of periodontitis, understanding the mechanism of the pathogenesis will allow for development of treatment for periodontal disease and hopefully eradicate Porphyromonas gingivalis.

Genome structure

Select a strain for which genome information (e.g. size, plasmids, distinct genes, etc.) is available.

Cell structure and metabolism

Cell wall, biofilm formation, motility, metabolic functions.

Ecology

Aerobe/anaerobe, habitat (location in the oral cavity, potential other environments) and microbe/host interactions.

Pathology

Do these microorganisms cause disease in the oral cavity or elsewhere?

Application to biotechnology

Bioengineering, biotechnologically relevant enzyme/compound production, drug targets,…

Current research

Summarise some of the most recent discoveries regarding this species.

References

References examples

1. Sahm, K., MacGregor, B.J., Jørgensen, B.B., and Stahl, D.A. (1999) Sulphate reduction and vertical distribution of sulphate-reducing bacteria quantified by rRNA slotblot hybridization in a coastal marine sediment. Environ Microbiol 1: 65-74.

2. Human Oral Microbiome

This page is written by Jovin Choo Jia Ying for the MICR3004 course, Semester 2, 2016