Vibrio cholerae pathogenesis

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Vibrio cholerae is the causative agent of the diarrheal disease cholera. A disease affecting 2.8 million people per year and resulting in the deaths of 91,000, cholera is most common in areas with high population density and low sanitation quality.[1] [2]

Colonization of the Human Small Intestine

ToxR and ToxT Regulon

Toxin-Coregulating Pilus

References

[1] Reidl, J. and K.E. Klose, Vibrio cholerae and cholera: out of the water and into the host. Fems Microbiology Reviews, 2002. 26(2): p. 125-139.
[2] Ali, M., et al., The global burden of cholera. Bulletin of the World Health Organization, 2012. 90(3): p. 209-218.

Edited by Tina Solvik, a student of Suzanne Kern in BIOL168L (Microbiology) in The Keck Science Department of the Claremont Colleges Spring 2015.