West Nile Virus in Birds

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West Nile Virus, of the family Flaviviridae, is a zoonotic disease that infects many species, including humans, throughout the world. Birds are the virus’s primary natural reservoir, where they act as the amplifier host. but their host competency (their ability to perpetuate the virus' development and spread) and response to infection varies between species; they can have diverging viral loads, viremia, viral shedding, clinical signs, and morbidity. Many factors may affect a particular organism and/or species’ susceptibility and response to infection, based on their life histories, immune-response capabilities, previous immunities, breeding systems, genetics, and stress levels. Birds vary widely in how they are affected by West Nile Virus.

Initial Infection

West Nile Virus transmission cycle. From CDC.


Birds may become infected with West Nile Virus in multiple ways. The most common occurrence is through a mosquito vector. However, studies have shown that they may contract the infection through eating infected organisms, direct contact, or fecal contact.

Subsection: Mosquito Vectors: Blah blah mosquitos usually something something Oral Transmission: By ingesting infected mice or other birds, a carnivorous bird may present viremia.



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Overall paper length should be 3,000 words, with at least 3 figures with data.



Species Susceptibilities and Competence


Table 1. West Nile Virus Host Competency of 25 Species of Birds [1 for now].
Species Reservoir Competence Index*
Blue Jay 2.55
Common Grackle 2.04
House Finch 1.76
American Crow 1.62
House Sparrow 1.59
Ring-billed Gull 1.26
Black-billed Magpie 1.08
American Robin 1.08
Red-winged Blackbird 0.99
American Kestrel 0.93
Great Horned Owl 0.88
Killdeer 0.87
Fish Crow 0.73
Mallard 0.48
European Starling 0.22
Mourning Dove 0.19
Northern Flicker 0.06
Canada Goose 0.03
Rock Dove 0
American Coot 0
Japanese Quail 0
Northern Bobwhite 0
Ring-necked Pheasant 0
Monk Parakeet 0
*based on susceptibility, mean infectiousness and duration (days)



Chance of a mosquito picking up West Nile Virus from an infected host. Birds are the primary competent host for viral spread through mosquitoes, due to their high viral loads. Graphic from FAQ: West Nile Virus, July 2013. American Society For Microbiology, 2013. 5.



wow such a large table I wish I knew how to collapse it



Section 3


Include some current research in each topic, with at least one figure showing data.

Further Reading

[Sample link] Ebola Hemorrhagic Fever—Centers for Disease Control and Prevention, Special Pathogens Branch

References

[Sample reference] Takai, K., Sugai, A., Itoh, T., and Horikoshi, K. "Palaeococcus ferrophilus gen. nov., sp. nov., a barophilic, hyperthermophilic archaeon from a deep-sea hydrothermal vent chimney". International Journal of Systematic and Evolutionary Microbiology. 2000. Volume 50. p. 489-500.



1. Komar, N., S. Langevin, S. Hinten, N. Nemeth, E. Edwards, D. Hettler, B. Davis, R. Bowen, and M. Bunning. 2003. Experimental Infection of North American Birds with the New York 1999 Strain of West Nile Virus. Emerging Infectious Diseases 9(3): 311-322.



Edited by Leah Pomerantz, a student of Nora Sullivan in BIOL168L (Microbiology) in The Keck Science Department of the Claremont Colleges Spring 2014.