Zoonosis: Brucellosis in Animals and Humans
Introduction
By Hannah Wedig
Brucellosis is among the most common and highly contagious zoonoses. Zoonoses are diseases which can be transmitted from animals to humans. [1] In the case of brucellosis, mammals – domestic, wild, terrestrial, and marine – are capable of transmitting the disease. [1] [2] Brucellosis is caused by certain species of bacteria in the genus Brucella, the most common and virulent of which are B. melitensis, B. suis, and B. abortus (Figure 1). [3] [4] The genus Brucella is within the class α-Proteobacteria, which includes many bacterial parasites of both plants and animals. [5] All Brucella are miniscule (≈ 0.5µm-1.5µm in diameter), sessile, Gram-negative coccobacilli, and are facultative intracellular pathogens (Figure 2) [6] [3]
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- ↑ 1.0 1.1 Seleem, M. N., Boyle, S. M., Sriranganathan, N. 2010. Brucellosis: A re-emerging zoonosis. Veterinary Microbiology 140:392–398.
- ↑ Taleski, V., Zerva, L., Kantardijev, T., Cvetnic, Z., Erski-Biljic, M. et al. 2002. An overview of the epidemiology and epizootiology of brucellosis in selected countries of Central and Southeast Europe. Veterinary Microbiology 90:147–155.
- ↑ 3.0 3.1 Hagan, W. A., Bruner, W. D. Hagan and Bruner’s Microbiology and Infectious Diseases of Domestic Animals: With Reference to Etiology, Epizootiology, Pathogenesis, Immunity, Diagnosis, and Antimicrobial Susceptibility. Ithaca: Comstock Publ., 1992. Print.
- ↑ Young, E. J., M.D. “Brucella species (Brucellosis).” Infectious Disease and Antimicrobial Agents. Antimicrobe, 2014 Web.
- ↑ Moreno, E. and Moriyon, I. 2002. Brucella melitensis: A nasty bug with hidden credentials for virulence. Proc. Natl. Acad. Sci. USA. 99:1–3.
- ↑ Godfroid, J., Garin-Bastuji, B., Saegerman, C., Blasco, J. M. 2013. Brucellosis in terrestrial wildlife. Rev. sci. tech. Off. int. Epiz., 32:27–42.
- ↑ Retrospective and prospective perspectives on zoonotic brucellosis. 2014. Moreno, E. Front Microbiol. 5: 213.
- ↑ "Brucella Melitensis." Database of Bacterial Food Pathogen. Birla Institute of Scientific Research, 2015.
- ↑ Brucellosis in terrestrial wildlife. 2013. Godfroid, J., Garin-Bastuji, B., Saegerman, C., Blasco, J. M. Rev. sci. tech. Off. int. Epiz. 32 (1): 27-42
- ↑ Ariza, J., Bosilkovski, M., Cascio, A., Colmenero, J. D. et al. "Perspectives for the Treatment of Brucellosis in the 21st Century: The Ioannina Recommendations." 2008. PLoS Med 4(12): e317
- ↑ Retrospective and prospective perspectives on zoonotic brucellosis. 2014. Moreno, E. Front Microbiol. 5: 213.
- ↑ Retrospective and prospective perspectives on zoonotic brucellosis. 2014. Moreno, E. Front Microbiol. 5: 213.
- ↑ Hodgkin, J. and Partridge, F.A. "Caenorhabditis elegans meets microsporidia: the nematode killers from Paris." 2008. PLoS Biology 6:2634-2637.
- ↑ Bartlett et al.: Oncolytic viruses as therapeutic cancer vaccines. Molecular Cancer 2013 12:103.
Authored for BIOL 238 Microbiology, taught by Joan Slonczewski, 2017, Kenyon College.