Uploads by Kaplanse

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File list
Date Name Thumbnail Size Description Versions
18:05, 24 April 2013 Streptomyces coelicolor.jpeg (file) 235 KB A light bright-field light micrograph of Streptomyces coelicolor, a gram-positive actinobacterium that produces a variety of secondary metabolites. 1
03:19, 23 April 2013 NRPS Biosynthesis.png (file) 45 KB Biosynthesis of surfactin via NRPS. Each module is made up of at least three "core domains" in addition to other modifying enzymes. NRPS allow for the biosynthesis of peptides in the absence of both ribosomes and mRNA. 1
03:12, 23 April 2013 Epothilone Biosynthesis.gif (file) 16 KB The biosynthesis of epothilone, a novel anticancer compound. Notably, biosynthesis incorporates both PKSs (modules EPOS A, C, D, E, and F) and NRPSs (module EPOS P), illustrating the functional similarities between the two classes of enzymatic machinery. 1
03:09, 23 April 2013 PKS Biosynthesis.png (file) 1.64 MB Biosynthesis of 6-deoxythronolide in Erythromycin. Each catalytic module performs a specified chemical reaction that incorporates a ketone substrate into the growing PK chain. Sequential Claisen condensation reactions drive the elongation of the chai... 1