Talk:Opportunistic Infections Caused by Serratia marcescens

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I found this topic to be very interesting! All of the bases seemed to be covered, from treatment and prevention to antibiotic resistance. I also like the case studies and examples provided, as they add another dimension to the scientific aspect of infection. Are there any definitive symptoms of this pathogen that differ from other infections, or can we only tell that it is in fact S. marcescens by a biopsy?


Very good job with research on this topic--I can tell you know your stuff. I did have a couple of notes for things to look at. First, check on the citation format--I was under the impression that we were doing the Biology department's form of author, date style, which is different from your citations. Second, I didn't quite follow the last paragraph of the Introduction. I also didn't understand the two sentences following the lead in "The epidemiologic[al] report..." in the section titled "Cases in Humans". Along the same lines (and in the same section), the sentence "The skin lesions had appeared 4 weeks and neither topical nor oral antibiotic treatment with pencillin improved the lesions" is a little redundant--is there any way to rework this to make it more powerful? Third, is it possible to rework the "Treatment and Prevention" section, or to combine this with the section titled "Diagnosis"? The latter is quite short and the former seems very disjointed.


Lastly, some nitpicky things:
--Check and make sure you've italicized S. marcescens every time you use it
--In the third paragraph of the introduction, you may want to add "by S. marscens", because it seems as though you're just listing general types of nosocomial infections (especially with a list that long!)
--The word "personnel" has 2 Ns and 1 l
--Did you mean to say "horizontal transmission"? That seems like an odd word choice
--Define NICU and PICU earlier--as it stands now, you define them after you've already used the terms multiple times
--The sentence ""For instance, six dogs were infected and this was the first documentation of nosocomial Serratia spp septicemia in 1973" is a bit awkwardly phrased. Maybe rework it a bit?
--"Rapid" in the section on human cases should be in its adverbial form, "rapidly"
--In the "Hydrophobicity" section, you don't need the "thus" in the second-to-last sentence, nor should you have a comma in the first sentence of the second paragraph (after the word "fimbriae").

Some questions:
--What is the LPS "core" that you mention in the "Hydrophobicity" section made from?
--Why does it matter that S. marcescens is resistant to beta-lactamase?
--There is no comma after the word "although" unless you have a parenthetical statement following it.

All in all, great job. I look forward to reading it when you've finished!