Tobacco Mosaic Virus Uses In Pharmaceutical Research: Difference between revisions
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Every point of information REQUIRES CITATION using the citation tool shown above. | Every point of information REQUIRES CITATION using the citation tool shown above. | ||
== | ==Discovery== | ||
Include some current research, with at least one figure showing data.<br> | Include some current research, with at least one figure showing data.<br> | ||
<br> | <br> | ||
<ref>[https://www.apsnet.org/edcenter/intropp/lessons/viruses/Pages/TobaccoMosaic.aspx<i>Tobacco Mosaic Virus</i>]</ref> | <ref>[https://www.apsnet.org/edcenter/intropp/lessons/viruses/Pages/TobaccoMosaic.aspx<i>Tobacco Mosaic Virus</i>]</ref> | ||
[[Image:TMV.jpg|thumb|300px|right|Tobacco Mosaic Virus infection of neighboring cells [https://www.apsnet.org/edcenter/intropp/lessons/viruses/Pages/TobaccoMosaic.aspx].]] | [[Image:TMV.jpg|thumb|300px|right|Tobacco Mosaic Virus infection of neighboring cells [https://www.apsnet.org/edcenter/intropp/lessons/viruses/Pages/TobaccoMosaic.aspx].]] | ||
== | ==Structure== | ||
Include some current research, with at least one figure showing data.<br> | Include some current research, with at least one figure showing data.<br> | ||
<br> | <br> | ||
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[[Image:SEMelectrodesTMV.gif|thumb|300px|right|Micropillers of the TMV on electrodes in a microbattery [https://pubs.acs.org/doi/full/10.1021/nn301981p].]] | [[Image:SEMelectrodesTMV.gif|thumb|300px|right|Micropillers of the TMV on electrodes in a microbattery [https://pubs.acs.org/doi/full/10.1021/nn301981p].]] | ||
== | ==Transmission== | ||
<ref>[https://www.ncbi.nlm.nih.gov/pubmed/28713855<i>High Aspect Ratio Nanotubes Formed by Tobacco Mosaic Virus for Delivery of Photodynamic Agents Targeting Melanoma</i>]</ref> | <ref>[https://www.ncbi.nlm.nih.gov/pubmed/28713855<i>High Aspect Ratio Nanotubes Formed by Tobacco Mosaic Virus for Delivery of Photodynamic Agents Targeting Melanoma</i>]</ref> | ||
[[Image:TMVmelanoma.jpg|thumb|300px|right|TMV nanocarrier plus photosensitizer lead to cell death [https://www.ncbi.nlm.nih.gov/pubmed/28713855].]] | [[Image:TMVmelanoma.jpg|thumb|300px|right|TMV nanocarrier plus photosensitizer lead to cell death [https://www.ncbi.nlm.nih.gov/pubmed/28713855].]] | ||
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[[Image:VaccineTMV.PNG|thumb|300px|right|Two different designes for the TMV nanocarrier [https://www.ncbi.nlm.nih.gov/pubmed/26098553].]] | [[Image:VaccineTMV.PNG|thumb|300px|right|Two different designes for the TMV nanocarrier [https://www.ncbi.nlm.nih.gov/pubmed/26098553].]] | ||
== | ==Epidemiology== | ||
== | ==Using TMV in Drug Delivery== | ||
== | ==TMV as a Treatment for Melanoma== | ||
== | ==Tobacco Mosaic Virus (TMV) as a Vaccine== | ||
== | ==TMV Scaffolds Used to Make Other Nanoparticles== | ||
== | ==TMV Applications in Micromachines== | ||
==Conclusions== | |||
==References== | ==References== |
Revision as of 15:47, 25 April 2018
Tobacco Mosaic Virus Uses in Pharmaceutical Research
Section
By Michael Itschner II
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Legend/credit: Electron micrograph of the Ebola Zaire virus. This was the first photo ever taken of the virus, on 10/13/1976. By Dr. F.A. Murphy, now at U.C. Davis, then at the CDC.
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Introduction
The Tobacco Mosaic Virus (TMV) has been well researched since it has been defined a virus in 1898 by Martinus Beijerinck. TMV has been used as a model virus for a teaching tool in biology classes and as a scaffold for drug delivery mechanisms. Since there has been much research done on this virus previously, TMV has a widely accepted and well-defined structure. The scaffolding of this virus is of particular interest because its protein base serves as a template for precise targeting of surface groups on cells. Plant viruses have drawn more attention since they are unable to infect mammalian hosts and have good blood and tissue compatibility in mammals. TMV is also to biodegradable and able to be cleaned out of non-target tissues and organs, making TMV a probable candidate for the targeting and delivery of therapeutics to mammals. [1]
Every point of information REQUIRES CITATION using the citation tool shown above.
Discovery
Include some current research, with at least one figure showing data.
[2]
Structure
Include some current research, with at least one figure showing data.
[3]
Transmission
Epidemiology
Using TMV in Drug Delivery
TMV as a Treatment for Melanoma
Tobacco Mosaic Virus (TMV) as a Vaccine
TMV Scaffolds Used to Make Other Nanoparticles
TMV Applications in Micromachines
Conclusions
References
- ↑ Tobacco Mosaic Virus Delivery of Phenanthriplatin for Cancer therapy
- ↑ Tobacco Mosaic Virus
- ↑ Hierarchical Three-Dimensional Microbattery Electrodes Combining Bottom-Up Self-Assembly and Top-Down Micromachining
- ↑ High Aspect Ratio Nanotubes Formed by Tobacco Mosaic Virus for Delivery of Photodynamic Agents Targeting Melanoma
- ↑ Development of a Multivalent Subunit Vaccine against Tularemia Using Tobacco Mosaic Virus (TMV) Based Delivery System
Authored for BIOL 238 Microbiology, taught by Joan Slonczewski, 2018, Kenyon College.