Cryptococcus neoformans: Difference between revisions

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''C. neoformans v. neoformans'', ''C. neoformans v. grubii''. A third variety, ''C. neoformans v. gattii'', is now considered a distinct species, ''[[Cryptococcus gattii]]''.
''C. neoformans v. neoformans'', ''C. neoformans v. grubii''. A third variety, ''C. neoformans v. gattii'', is now considered a distinct species, ''[[Cryptococcus gattii]]''.


==Pathogenesis==
==Description==
===Virulence factors===
===Physical characteristics===
 
''C. neoformans'' is a
====Diphtheria toxin====
Diphtheria toxin is an exotoxin that prevents protein synthesis through inactivation of eEF2 (eukaryotic elongation factor 2). This is done by ADP-ribosylating the amino acid diphthamide, inhibiting RNA translation.
 
===Mechanism===
 
====Adherence====
 
====Invasion of the cell====
 
====Encountering macrophages====


==Clinical features==
==Clinical features==

Revision as of 21:08, 22 July 2015

University of Oklahoma Study Abroad Microbiology in Arezzo, Italy[1]
File:Cdiphtheriametachromatic.jpg
C. diphtheriae bacteria, in green, showing metachromatic granules on the ends of the cell. From: http://textbookofbacteriology.net/diphtheria.html

Classification

Higher order taxa

Eukaryota (Kingdom); Fungi (Domain); Basidiomycota (Phylum); Tremellomycetes (Class); Tremellales (Order); Tremellaceae (Family); Cryptococcus (Genus)

Species

C. neoformans v. neoformans, C. neoformans v. grubii. A third variety, C. neoformans v. gattii, is now considered a distinct species, Cryptococcus gattii.

Description

Physical characteristics

C. neoformans is a

Clinical features

Symptoms typically begin 2 to 7 days after infection. Diphtheria is characterized by sore throat, slight fever, fatigue, and an adherent membrane (called a pseudomembrane) on the tonsils, pharynx, and/or nasal cavity. Diphtheria toxin produced by C. diphtheriae can cause myocarditis, polyneuritis, and other systemic toxic effects. A milder form of diphtheria can be restricted to the skin.

Diagnosis

Treatment

Prevention

Host immune response

References