Vax1 Homeobox Genes and Mammalian Embryo Development

Introduction

Vax1 is a novel homeobox gene discovered 1998 by a group of researchers in Max Planck Institute for Biophysical Chemistry in the human and mouse genome, crucial to the development of the vertebrate forebrain, olfactory, and visual systems of mammals. Vax1 is a gene that directly regulates the activation of transcriptional factors such as Emx1, which is a protein coding gene that is crucial in the synthesis of the neural and ciliary structure of the frontal systems of the roof and archipallium of the brain during early development. Through the use of interspecific backcross analysis in mice, crossing a hybrid with one of its parents or an individual genetically similar to its parent , the Vax1 genome was accurately mapped on the distal regions of the mouse chromosomal region.

Classification and Structure

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Function

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Conclusion

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References

Edited by Logan Gusmano, student of Joan Slonczewski for BIOL 116 Information in Living Systems, 2021, Kenyon College.