Pseudomonas entomophila: Difference between revisions

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===Genus===  
===Genus===  


Pseudomonas entomophila
Pseudomonas entomophila
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==Description and significance==
==Description and significance==
P. entomophila is a bacterial strain isolated from a fruit fly from Guadeloupe. Upon ingestion it kills Drosophila melanogaster larvae and adults, as well as insects from other orders. Its persistence in the insect gut triggers a local and systemic immune response in the insect, making it a useful model for insect pathogenesis; indeed it is the first natural pathogen of D.melanogaster known. P. entomophila is unusual in that it does have a type III or type IV secretion system, one of which is usually found in pathogens. The mode by which it kills is not clear, although the genome encodes several insecticidal toxins, a diffusible haemolytic activity, several lipases, a number of extracellular proteases and potential adhesions which cluster with type I or II secretion system proteins. It may also be able to produce hydrogen cyanide and novel secondary metabolites which could contribute to its lethality.
Pseudomonas entomophila is a Gram negative bacteria, found in the soil and first isolated from the species Drosophila melanogaster. Once ingested, causes lethality in Drosophila melanogaster larvae and adults. Pseudomonas entomophila's significance is that its the first known pathogen for Drosophila melanogaster. Pseudomonas entomophila's genome encodes insecticidal toxins, a diffusible haemolytic activity, lipases, extracellular proteases, and potential adhesions which cluster with type I or II secretion system proteins. Being relatively harmless to plant life, Pseudomonas entomophila may be used for future insecticides.


==Genome structure==
==Genome structure==

Revision as of 22:36, 2 May 2007

Template:Biorealm genus

Classification

Higher order taxa

Bacteria, Proteobacteria, Gammaproteobacteria, Pseudomonadales, Pseudomonadaceae, Pseudomonas

Genus

Pseudomonas entomophila


NCBI: Taxonomy

Description and significance

Pseudomonas entomophila is a Gram negative bacteria, found in the soil and first isolated from the species Drosophila melanogaster. Once ingested, causes lethality in Drosophila melanogaster larvae and adults. Pseudomonas entomophila's significance is that its the first known pathogen for Drosophila melanogaster. Pseudomonas entomophila's genome encodes insecticidal toxins, a diffusible haemolytic activity, lipases, extracellular proteases, and potential adhesions which cluster with type I or II secretion system proteins. Being relatively harmless to plant life, Pseudomonas entomophila may be used for future insecticides.

Genome structure

DNA; circular; Length: 5,888,780 nt; Replicon Type: chromosome

Cell structure and metabolism

Gram negative. Flagella present

Ecology

Describe any interactions with other organisms (included eukaryotes), contributions to the environment, effect on environment, etc.

Pathology

How does this organism cause disease? Human, animal, plant hosts? Virulence factors, as well as patient symptoms.

Application to Biotechnology

Does this organism produce any useful compounds or enzymes? What are they and how are they used?

Current Research

Enter summaries of the most recent research here--at least three required

References

PubMed=16699499; [ NCBI , Israel , Japan ]

Vodovar N., Vallenet D., Cruveiller S., Rouy Z., Barbe V., Acosta C., Cattolico L., Jubin C., Lajus A., Segurens B., Vacherie B., Wincker P., Weissenbach J., Lemaitre B., Medigue C., Boccard F. "Complete genome sequence of the entomopathogenic and metabolically versatile soil bacterium Pseudomonas entomophila." Nat. Biotechnol. 24:673-679(2006).

EBI Proteome Analysis page


Edited by student of Jason Kim

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