Cytomegalovirus in post transplant patients: Difference between revisions

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[[Image:Viron.gif‎|thumb|300px|right|Figure 2. The CMV virion has a similar composition to all human herpes viruses (HHV). [http://detadoctor.com/deta-ap/cytomegalovirus/].]]
[[Image:Viron.gif‎|thumb|300px|right|Figure 2. The CMV virion has a similar composition to all human herpes viruses (HHV). [http://detadoctor.com/deta-ap/cytomegalovirus/].]]
[[Image:Cancer.jpg|thumb|300px|right|Figure 3. HCMV infection induces tumor progression in human cells by decreasing the sensitivity of neuroblastoma cells to apoptotic stimuli and through the induction of angiogenesis. This results in the mass growth of tumor cells along with lowered sensitivity to chemotherapeutic agents.  [http://www.sciencedirect.com/science/article/pii/S1471491403002478.]]


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Revision as of 02:05, 21 April 2015

Introduction

Picture of the CMV virus. [1].


Introduce the topic of your paper. What microorganisms are of interest? Habitat? Applications for medicine and/or environment?


The cytomegalovirus (CMV) is part of the Herpesviridae viral family also known as herpesviruses. Herpesviruses share common characteristics including the ability to remain metabolically inert within the human body for extended periods of time. The human cytomegalovirus (HCMV) also known as Human herpesvirus 5 (HHV-5) is a species that causes infections typically associated with the salivary gland. CMV is a common virus where about 50%-100% of the general adult population is infected. However, most people who are infected are unaware since the virus is typically dormant in healthy individuals. Those with compromised immune systems undergo symptoms similar to mononucleosis, a viral infection caused by the Epstein-Barr virus (another herpes virus). Immunocompromised individuals such as organ transplant recipients and AIDS patients…

Figure 2. The CMV virion has a similar composition to all human herpes viruses (HHV). [2].
Figure 3. HCMV infection induces tumor progression in human cells by decreasing the sensitivity of neuroblastoma cells to apoptotic stimuli and through the induction of angiogenesis. This results in the mass growth of tumor cells along with lowered sensitivity to chemotherapeutic agents. [http://www.sciencedirect.com/science/article/pii/S1471491403002478.



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Legend/credit: Picture of the CMV virus. [3].
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HCMV role in cancer

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Section 2

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Section 3

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References

[1] Hodgkin, J. and Partridge, F.A. "Caenorhabditis elegans meets microsporidia: the nematode killers from Paris." 2008. PLoS Biology 6:2634-2637.

Authored for BIOL 238 Microbiology, taught by Joan Slonczewski, 2015, Kenyon College.

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