Genetics of Multiple Sclerosis: Difference between revisions
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==Section 2 Microbiome== | ==Section 2 Microbiome== | ||
There has been a great deal of research that has been done in regards to the role that viruses might play on the contraction of multiple sclerosis. The strongest piece of evidence that points to this idea is that around 90-95% of the people who have multiple sclerosis, are also found to have certain proteins in their spinal fluids that are commonly found in the spinal fluids of patients with nervous system diseases. These diseases are known to be reactions to the presence of certain viruses. | There has been a great deal of research that has been done in regards to the role that viruses might play on the contraction of multiple sclerosis. The strongest piece of evidence that points to this idea is that around 90-95% of the people who have multiple sclerosis, are also found to have certain proteins in their spinal fluids that are commonly found in the spinal fluids of patients with nervous system diseases. These diseases are known to be reactions to the presence of certain viruses. | ||
Alberto Ascherio from the Harvard School of Public Health has been studying the impact that the Epstein-Barr virus has on the development of multiple sclerosis. He found that antibodies, which were produced by the patient’s immune system as a result of the infection by the virus, were greater in number in the patients who had multiple sclerosis compared to the control group. Ascherio was able to find that the presence of the Epstein-Barr virus led to a significant increase in the risk of having multiple sclerosis. Furthermore, Emmanuelle Waubant from the University of California at San Francisco, studied children who either had early multiple sclerosis or were at an increased risk of contracting it. Waubant found strong evidence correlating the Epstein-Barr virus and the presence or risk thereof of contracting multiple sclerosis. | |||
As stated previously, no virus has yet been shown to fundamentally cause multiple sclerosis. One of the reasons for this is because it is very hard for researchers to actually prove that a disease causes multiple sclerosis to form in the body. They must first prove that the virus had been in the body before the development of multiple sclerosis, and then they must prove that the virus is causing multiple sclerosis. | As stated previously, no virus has yet been shown to fundamentally cause multiple sclerosis. One of the reasons for this is because it is very hard for researchers to actually prove that a disease causes multiple sclerosis to form in the body. They must first prove that the virus had been in the body before the development of multiple sclerosis, and then they must prove that the virus is causing multiple sclerosis. | ||
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Revision as of 11:02, 2 December 2019
Introduction
My topic is multiple sclerosis. Multiple sclerosis is a type of disease that attacks the immmune system, commonly referred to as an auto immune disease. Multiple sclerosis particularly affects the myelin sheath of the spinal cord, which then negatively impacts communication between the brain and other parts of the body.
Select a topic about genetics or evolution in a specific organism or ecosystem.
The topic must include one section about microbes (bacteria, viruses, fungi, or protists). This is easy because all organisms and ecosystems have microbes.
Compose a title for your page.
Type your exact title in the Search window, then press Go. The MicrobeWiki will invite you to create a new page with this title.
Open the BIOL 116 Class 2019 template page in "edit."
Copy ALL the text from the edit window.
Then go to YOUR OWN page; edit tab. PASTE into your own page, and edit.
Section 1 Genetics
Multiple sclerosis is an autoimmune disease with a great deal of mystery surrounding it. The exact cause of multiple sclerosis is still unknown. Having said that, multiple sclerosis has been shown to not be able to be passed down from generation to generation, implying that it is not an inherited disease. However, there still remains the risk of the disease being inherited. The genes that appear to be linked to the presence of multiple sclerosis are as follows: HLA class I and class II, T-cell-receptor α, CTLA4, ICAM1, and SH2D2A. There is an estimated 200 genes that appear to be linked to multiple sclerosis, but there is a great deal of ambiguity surrounding the idea of what precise role these genes play in the contribution to multiple sclerosis.
Sample citations: [1]
[2]
A citation code consists of a hyperlinked reference within "ref" begin and end codes.
Section 2 Microbiome
There has been a great deal of research that has been done in regards to the role that viruses might play on the contraction of multiple sclerosis. The strongest piece of evidence that points to this idea is that around 90-95% of the people who have multiple sclerosis, are also found to have certain proteins in their spinal fluids that are commonly found in the spinal fluids of patients with nervous system diseases. These diseases are known to be reactions to the presence of certain viruses.
Alberto Ascherio from the Harvard School of Public Health has been studying the impact that the Epstein-Barr virus has on the development of multiple sclerosis. He found that antibodies, which were produced by the patient’s immune system as a result of the infection by the virus, were greater in number in the patients who had multiple sclerosis compared to the control group. Ascherio was able to find that the presence of the Epstein-Barr virus led to a significant increase in the risk of having multiple sclerosis. Furthermore, Emmanuelle Waubant from the University of California at San Francisco, studied children who either had early multiple sclerosis or were at an increased risk of contracting it. Waubant found strong evidence correlating the Epstein-Barr virus and the presence or risk thereof of contracting multiple sclerosis.
As stated previously, no virus has yet been shown to fundamentally cause multiple sclerosis. One of the reasons for this is because it is very hard for researchers to actually prove that a disease causes multiple sclerosis to form in the body. They must first prove that the virus had been in the body before the development of multiple sclerosis, and then they must prove that the virus is causing multiple sclerosis.
Conclusion
Overall text length should be at least 1,000 words (before counting references), with at least 2 images. Include at least 5 references under Reference section.
References
Edited by [Thomas Kallarakal], student of Joan Slonczewski for BIOL 116 Information in Living Systems, 2019, Kenyon College.
