CTXφ Bacteriophage: Difference between revisions
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==Overview== | ==Overview== | ||
The CTXφ bacteriophage ( | The CTXφ bacteriophage (or CTX<i>phi</i> bacteriophage) is a lysogenic, single-stranded DNA filamented phage that is responsible for turning the previously non-infectious <i>Vibrio cholerae</i> into a highly pathogenic microbe that causes disease in humans.<ref name = Davis>Davis, B. M., Kimsey, H. H., Chang, W., & Waldor, M. K. (1999). "The Vibrio cholerae O139 Calcutta bacteriophage CTXφ is infectious and encodes a novel repressor." <i>Journal of Bacteriology</i>, 181(21), 6779-6787.</ref>,<ref name = Ochman>Ochman, H., Lawrence, J. & Groisman, E. (2000). "Lateral gene transfer and the nature of bacterial innovation." <i>Nature</i> 405, 299–304. https://doi.org/10.1038/35012500.</ref> | ||
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Revision as of 01:57, 11 December 2020
Overview
The CTXφ bacteriophage (or CTXphi bacteriophage) is a lysogenic, single-stranded DNA filamented phage that is responsible for turning the previously non-infectious Vibrio cholerae into a highly pathogenic microbe that causes disease in humans.[1],[2]
Genetic Material
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Infection, Replication & Lysing of Host Cell
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Filename: PHIL_1181_lores.jpg
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Legend/credit: Electron micrograph of the Ebola Zaire virus. This was the first photo ever taken of the virus, on 10/13/1976. By Dr. F.A. Murphy, now at U.C. Davis, then at the CDC.
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CT & non-CT Toxins
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Conclusion
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References
- ↑ Davis, B. M., Kimsey, H. H., Chang, W., & Waldor, M. K. (1999). "The Vibrio cholerae O139 Calcutta bacteriophage CTXφ is infectious and encodes a novel repressor." Journal of Bacteriology, 181(21), 6779-6787.
- ↑ Ochman, H., Lawrence, J. & Groisman, E. (2000). "Lateral gene transfer and the nature of bacterial innovation." Nature 405, 299–304. https://doi.org/10.1038/35012500.
- ↑ Hodgkin, J. and Partridge, F.A. "Caenorhabditis elegans meets microsporidia: the nematode killers from Paris." 2008. PLoS Biology 6:2634-2637.
- ↑ Bartlett et al.: Oncolytic viruses as therapeutic cancer vaccines. Molecular Cancer 2013 12:103.
Edited by Tara Cerny, student of Joan Slonczewski for BIOL 116 Information in Living Systems, 2019, Kenyon College.
