Finegoldia magna: Difference between revisions
Line 72: | Line 72: | ||
[6] [https://journals-asm-org.proxyiub.uits.iu.edu/doi/full/10.1128/CMR.11.1.81 Murdoch, D.A. "Gram-Positive Anaerobic Cocci". ''American Society for Microbiology: Clinical Microbiology Reviews''. 1998. '''11''':1. pp. 81-120.] | [6] [https://journals-asm-org.proxyiub.uits.iu.edu/doi/full/10.1128/CMR.11.1.81 Murdoch, D.A. "Gram-Positive Anaerobic Cocci". ''American Society for Microbiology: Clinical Microbiology Reviews''. 1998. '''11''':1. pp. 81-120.] | ||
[7] [https://www-microbiologyresearch-org.proxyiub.uits.iu.edu/content/journal/ijsem/10.1099/00207713-33-4-683 Ezaki, T., N. Yamamoto, K. Ninomiya, S. Suzuki, E. Yabuuchi | [7] [https://www-microbiologyresearch-org.proxyiub.uits.iu.edu/content/journal/ijsem/10.1099/00207713-33-4-683 Ezaki, T., N. Yamamoto, K. Ninomiya, S. Suzuki, E. Yabuuchi. "Transfer of Peptococcus indolicus, Peptococcus asaccharolyticus, Peptococcus prevotii, and Peptococcus magnus to the Genus Peptostreptococcus and Proposal of Peptostreptococcus tetradius sp. nov.". ''International Journal of Systematic and Evolutionary Microbiology''. 1983. '''33''':4. pp. 683-698.] | ||
[8] [https://cdnsciencepub-com.proxyiub.uits.iu.edu/doi/abs/10.1139/w98-016 Ng, J., L. Ng, D. Mayrand, J.R. Dillon. "Aminopeptidase activities in Peptostreptococcus spp. are statistically correlated to gelatin hydrolysis". ''Canadian Journal of Microbiology''. 1998. '''4''':3. pp. 303-306.] | |||
==Author== | ==Author== |
Revision as of 01:56, 21 April 2022
Classification
Domain: Bacteria
Phylum: Firmicutes
Class: Clostridia
Order: Eubacteriales
Family: Peptoniphilaceae
Genus: Finegoldia
Species
Finegoldia magna [3]
NCBI: Taxonomy [4] |
Description and Significance
Describe the appearance, habitat, etc. of the organism, and why you think it is important.
"Finegoldia magna" is a slow-growing, non-spore-forming, Gram-positive anaerobic coccus (GPAC) bacteria.
- The Genus namesake is in remembrance of the American microbiologist Sydney Martin Finegold.
Genome Structure
Describe the size and content of the genome. How many chromosomes? Circular or linear? Other interesting features? What is known about its sequence?
Cell Structure, Metabolism and Life Cycle
Interesting features of cell structure; how it gains energy; what important molecules it produces.
Cell Structure
- Finegoldia magna is a Gram-positive anaerobic coccus (GPAC) bacteria, in which "coccus" indicates a spherical cell shape. Gram-positive indicates a bacterium with thick petidoglycan cell walls.
- It has a cell size that varies from 0.8 µm and 1.6 µm in diameter, and cells occur predominantly in clusters but occasionally in short chains or pairs, as in Figure 2.
- This bacteria has sortase-dependent pilli, which are hair-like structures characteristic of bacterial adhesion and colonization (i.e., important for biofilm formation) as well as host infection. [5]
Metabolism
- As an anaerobe, F. magna requires an oxygen-free environment to grow. However, in a 1998 experiment by Murdoch et al., F. magna isolates were plated on agar and exposed to air. After 48 hours, some clusters survived, indicating some level of oxygen tolerance. [6]
- F. magna produces acetic acid as a major fermentation product. It produces weak acid utilizing fructose, while a few strains use glucose as a carbon source. Peptones and amino acids are also used an energy sources. It can produce ammonia from glycine, threonine, and serine. [7]
- Aminopeptidases (i.e. catalyze cleavage of amino acids) have been reported but are not well-studied. [8]
Survival and Life Cycle
Ecology and Pathogenesis
Habitat; symbiosis; biogeochemical significance; contributions to environment. If relevant, how does this organism cause disease? Human, animal, plant hosts? Virulence factors, as well as patient symptoms.
References
Author
Page authored by Susan Reed, Nitesh Naren, Matt Millikin, students of Prof. Jay Lennon at Indiana University.