Pseudomonas entomophila
Classification
Higher order taxa
Bacteria, Proteobacteria, Gammaproteobacteria, Pseudomonadales, Pseudomonadaceae, Pseudomonas
Genus
Pseudomonas entomophila
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NCBI: Taxonomy |
Description and significance
P. entomophila is a bacterial strain isolated from a fruit fly from Guadeloupe. Upon ingestion it kills Drosophila melanogaster larvae and adults, as well as insects from other orders. Its persistence in the insect gut triggers a local and systemic immune response in the insect, making it a useful model for insect pathogenesis; indeed it is the first natural pathogen of D.melanogaster known. P. entomophila is unusual in that it does have a type III or type IV secretion system, one of which is usually found in pathogens. The mode by which it kills is not clear, although the genome encodes several insecticidal toxins, a diffusible haemolytic activity, several lipases, a number of extracellular proteases and potential adhesions which cluster with type I or II secretion system proteins. It may also be able to produce hydrogen cyanide and novel secondary metabolites which could contribute to its lethality.
Genome structure
DNA; circular; Length: 5,888,780 nt; Replicon Type: chromosome
Cell structure and metabolism
Gram negative. Flagella present
Ecology
Describe any interactions with other organisms (included eukaryotes), contributions to the environment, effect on environment, etc.
Pathology
How does this organism cause disease? Human, animal, plant hosts? Virulence factors, as well as patient symptoms.
Application to Biotechnology
Does this organism produce any useful compounds or enzymes? What are they and how are they used?
Current Research
Enter summaries of the most recent research here--at least three required
References
PubMed=16699499; [ NCBI , Israel , Japan ]
Edited by student of Jason Kim
