Variovorax durovernensis
BIO 330 - Variovorax durovernensis
Classification
Domain: Bacteria Phylum: Pseudomonadota Class: Betaproteobacteria Order: Burkholderiales Family: Comamonadaceae12
Species
NCBI:txid2832471
Description and Significance
Variovorax durovernensis is a gram-negative bacterium with a curved rod-like cellular morphology. This bacterium typically finds its habitat is soil but has been found in human infections specifically located in the aorta. Variovorax durovernensis is significant because of its role in medicine, potential technology advancements, and ecological health such as plant growth.
Genome Structure
Variovorax durovernensis is approximately 7,390,000 base pairs in size. Variovorax durovernensis has a single circular chromosome. In addition, Variovorax durovernensis has the feature to adapt to extreme environmental conditions and bioremediation. The sequence itself does not differ far from other Variovorax; however, Variovorax durovernensis has a unique sequence that provides a stronger ability to adapt to extreme environmental changes.
Cell Structure, Metabolism and Life Cycle
Variovorax durovernensis is a gram-negative bacterium that has a rod-like cellular morphology. Variovorax durovernensis typically receives energy through the process of aerobic respiration. Variovorax durovernensis contributes to life through degradation of environmental pollutants.
Ecology and Pathogenesis
V. durovernensis is typically found in an environment that is soil-based. The bacterium itself shares a symbiotic relationship with the surrounding plants within the soil habitat. V. durovernensis promotes growth and uptake of nutrients. Regarding biogeochemical significance, V. durovernensis performs bioremediation and allows the Recyling of the environment's natural pollutants.
Although V. durovernensis has been recently discovered to influence disease and overall virulence, V. durovernensis targets immunocompromised humans. V. durovernensis remains to have only been discovered in humans aortas and has only been known to cause fevers. V. durovernensis has a presentation of infection-like features.
References
Payne, L., Alcolea-Medina, A., Snell, L. B., Alder, C., Charalampous, T., Turnbull, J. D., Edgeworth, J. D., Batra, R., Klein, J. L., & Goodman, A. L. (2024). The first reported case of human infection with Variovorax durovernensis; a novel Variovorax sp. Isolated from the prosthetic aortic graft of a shepherd. Clinical Infection in Practice, 21, 100332. https://doi.org/10.1016/j.clinpr.2023.100332
https://www.ncbi.nlm.nih.gov/datasets/taxonomy/2832471/.
https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi
Alcolea-Medina A, Snell LB, Payne L, Alder CJ, Turnbull JD, Charalampous T, Bryan L, Klein JL, Edgeworth JD, Batra R, Goodman AL. Variovorax durovernensis sp. nov., a novel species isolated from an infected prosthetic aortic graft in a human. Int J Syst Evol Microbiol. 2023 Dec;73(12). doi: 10.1099/ijsem.0.006184. PMID: 38050797.
Ghimire, N., Kim, B., Lee, CM. et al. Comparative genome analysis among Variovorax species and genome guided aromatic compound degradation analysis emphasizing 4-hydroxybenzoate degradation in Variovorax sp. PAMC26660. BMC Genomics 23, 375 (2022). https://doi.org/10.1186/s12864-022-08589-3
Author
Page authored by Devin Wilson, KJ Fort, Nick Prewo, and Michael Sanders, students of Prof. Bradley Tolar at UNC Wilmington.
