Genetics of Multiple Sclerosis

Introduction

My topic is multiple sclerosis. Multiple sclerosis is a type of disease that attacks the immmune system, commonly referred to as an auto immune disease. Multiple sclerosis particularly affects the myelin sheath of the spinal cord, which then negatively impacts communication between the brain and other parts of the body. Select a topic about genetics or evolution in a specific organism or ecosystem.
The topic must include one section about microbes (bacteria, viruses, fungi, or protists). This is easy because all organisms and ecosystems have microbes.

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Open the BIOL 116 Class 2019 template page in "edit."
Copy ALL the text from the edit window.
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Image of multiple sclerosis affecting myelin sheath and the brain. Transmission electron microscope image taken by Dr. Tom Geisbert

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Filename: PHIL_1181_lores.jpg
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Pixel size: |300px|
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Legend/credit: Electron micrograph of the Ebola Zaire virus. This was the first photo ever taken of the virus, on 10/13/1976. By Dr. F.A. Murphy, now at U.C. Davis, then at the CDC.
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Section 1 Genetics

Multiple sclerosis is an autoimmune disease with a great deal of mystery surrounding it. The exact cause of multiple sclerosis is still unknown. Having said that, multiple sclerosis has been shown to not be able to be passed down from generation to generation, implying that it is not an inherited disease. However, there still remains the risk of the disease being inherited. The genes that appear to be linked to the presence of multiple sclerosis are as follows: HLA class I and class II, T-cell-receptor α, CTLA4, ICAM1, and SH2D2A. There is an estimated 200 genes that appear to be linked to multiple sclerosis, but there is a great deal of ambiguity surrounding the idea of what precise role these genes play in the contribution to multiple sclerosis.

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Section 2 Microbiome

Include some current research, with a second image.

Conclusion

Overall text length should be at least 1,000 words (before counting references), with at least 2 images. Include at least 5 references under Reference section.

References

Edited by [Thomas Kallarakal], student of Joan Slonczewski for BIOL 116 Information in Living Systems, 2019, Kenyon College.