BCG Vaccine

Introduction

Bacille Calmette Guerin (BCG) is the most common vaccine administered to combat tuberculosis disease in the world. (1) The vaccine contains a weakened live strain of Mycobacterium bovis (2), which is present in cows and shares a common ancestor with the human tubercule bacillus Mycobacterium tuberculosis (3). Similar to other vaccines, BCG induces the formation of antibodies from the harmless strain of Myobacterium bovis to help prevent tuberculosis (4). Although BCG remains as the primary vaccine against tuberculosis, it has only produced variable amounts of success. Additionally, the emergence of mycobacterial drug resistance has further jeopardized the effectiveness of BCG (5). Researchers are currently searching for a more effective way to treat tuberculosis disease, but no successful vaccine is expected for twenty years (1).

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Electron micrograph of the Ebola Zaire virus. This was the first photo ever taken of the virus, on 10/13/1976. By Dr. F.A. Murphy, now at U.C. Davis, then at the CDC.

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Legend/credit: Electron micrograph of the Ebola Zaire virus. This was the first photo ever taken of the virus, on 10/13/1976. By Dr. F.A. Murphy, now at U.C. Davis, then at the CDC.
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