Change in the Pharyngeal Microbial Environment after a Tonsillectomy

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By Lindsey Abramson

Introduction

Tonsillectomies, the surgical removal of the tonsils, are performed on individuals with chronic tonsillitis infections, recurrent strep throat, enlarged tonsils, and other issues such as cancerous cells (Brietzke and Andreoli, 2021). The goal of this radical procedure is the eradication of bacteria assuming antibiotics have been frequently used and failed / resistance was developed (Yildizoglu et al., 2015). Streptococcus pyogenes (also called group A streptococci, or GAS) is the causative agent bacterium of strep throat, one of the leading causes that push individuals towards an elective tonsillectomy (Slonczewski et al., 2024). Although viruses are also common, other problematic bacteria include: Staphylococcus aureus, Haemophilus influenzae, Streptococcus pneumoniae, Escherichia coli, and Pseudomonas aeruginosa (Yildizoglu et al., 2015).

Magnified 20,000X, this colorized scanning electron micrograph (SEM) depicts a grouping of methicillin resistant Staphylococcus aureus (MRSA) bacteria. See PHIL 617 for a black and white view of this image. Phoro credit: CDC.


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References

  1. ↑ 1.0 1.1 Hodgkin, J. and Partridge, F.A. "Caenorhabditis elegans meets microsporidia: the nematode killers from Paris." 2008. PLoS Biology 6:2634-2637.
  2. ↑ Bartlett et al.: Oncolytic viruses as therapeutic cancer vaccines. Molecular Cancer 2013 12:103.



Authored for BIOL 238 Microbiology, taught by Joan Slonczewski,at Kenyon College,2024

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