Faecalibacterium prausnitzii: Difference between revisions

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==Genome Structure==
==Genome Structure==
Describe the size and content of the genome.  How many chromosomes?  Circular or linear?  Other interesting features?  What is known about its sequence?
Faecalibacterium prausnitzii has two main phylogroups: Phylogroup I and Phylogroup II. Within these phylogroups there are different strains whose genomes have been documented in public databases with varying levels of assembly and annotation quality. When observing the genomes of Faecalibacterium prausnitzii, altogether the genome size has displayed variation, ranging from 2.68 million base pairs (Mbp) to 3.42 Mbp and having wide range of G-C% content varying from 54.9% to 63.0%. Most genomes have been constructed from draft assemblies, however one of the first strains to have a complete genome representation is F. prausnitzii strain A2-165 (Phylogroup II). This strain of F. prausnitzii has a circular genome containing 3.11 Mbp, 56.3% G-C content, 3,017 total genes, 2,790 coding genes, and 85 RNA genes.


In a study by Fitzgerald et al. (2018), 31 genomes of high-quality draft as well as complete genomes were used in a comparative genomics analysis to observe intraspecies diversity. The results displayed a high level of genome plasticity and a relatively low level of average nucleotide identity (ANI) between F. prausnitzii groups. Based on these observations, among others, Fitzgerald et al. have proposed to separate Faecalibacterium prausnitzii into two new species level taxa.


==Cell Structure, Metabolism and Life Cycle==
==Cell Structure, Metabolism and Life Cycle==
Interesting features of cell structure; how it gains energy; what important molecules it produces.
Interesting features of cell structure; how it gains energy; what important molecules it produces.

Revision as of 13:16, 29 April 2020

This student page has not been curated.

Classification

Domain: Bacteria; Phylum: Firmicutes; Class: Clostridia; Order: Clostridiales; Family: Ruminococcaceae; Genus: Faecalibacterium; Species: Faecalibacterium prausnitzii [Others may be used. Use NCBI link to find]

Species

NCBI: Taxonomy

Faecalibacterium prausnitzii

Description and Significance

Describe the appearance, habitat, etc. of the organism, and why you think it is important.

Genome Structure

Faecalibacterium prausnitzii has two main phylogroups: Phylogroup I and Phylogroup II. Within these phylogroups there are different strains whose genomes have been documented in public databases with varying levels of assembly and annotation quality. When observing the genomes of Faecalibacterium prausnitzii, altogether the genome size has displayed variation, ranging from 2.68 million base pairs (Mbp) to 3.42 Mbp and having wide range of G-C% content varying from 54.9% to 63.0%. Most genomes have been constructed from draft assemblies, however one of the first strains to have a complete genome representation is F. prausnitzii strain A2-165 (Phylogroup II). This strain of F. prausnitzii has a circular genome containing 3.11 Mbp, 56.3% G-C content, 3,017 total genes, 2,790 coding genes, and 85 RNA genes.

In a study by Fitzgerald et al. (2018), 31 genomes of high-quality draft as well as complete genomes were used in a comparative genomics analysis to observe intraspecies diversity. The results displayed a high level of genome plasticity and a relatively low level of average nucleotide identity (ANI) between F. prausnitzii groups. Based on these observations, among others, Fitzgerald et al. have proposed to separate Faecalibacterium prausnitzii into two new species level taxa.

Cell Structure, Metabolism and Life Cycle

Interesting features of cell structure; how it gains energy; what important molecules it produces.