Faecalibacterium prausnitzii
Classification
Domain: Bacteria; Phylum: Firmicutes; Class: Clostridia; Order: Clostridiales; Family: Ruminococcaceae [Others may be used. Use NCBI link to find]
Species
|
NCBI: Taxonomy |
Faecalibacterium prausnitzii
Description and Significance
Describe the appearance, habitat, etc. of the organism, and why you think it is important.
Genome Structure
Faecalibacterium prausnitzii has two main phylogroups: Phylogroup I and Phylogroup II. Within these phylogroups there are different strains whose genomes have been documented in public databases with varying levels of assembly and annotation quality. When observing the genomes of Faecalibacterium prausnitzii, altogether the genome size has displayed variation, ranging from 2.68 million base pairs (Mbp) to 3.42 Mbp and having wide range of G-C% content varying from 54.9% to 63.0%. Most genomes have been constructed from draft assemblies, however one of the first strains to have a complete genome representation is F. prausnitzii strain A2-165 (Phylogroup II). This strain of F. prausnitzii has a circular genome containing 3.11 Mbp, 56.3% G-C content, 3,017 total genes, 2,790 coding genes, and 85 RNA genes.
In a study by Fitzgerald et al. (2018), 31 genomes of high-quality draft as well as complete genomes were used in a comparative genomics analysis to observe intraspecies diversity. The results displayed a high level of genome plasticity and a relatively low level of average nucleotide identity (ANI) between F. prausnitzii groups. Based on these observations, among others, Fitzgerald et al. have proposed to separate Faecalibacterium prausnitzii into two new species level taxa.
Cell Structure, Metabolism and Life Cycle
Interesting features of cell structure; how it gains energy; what important molecules it produces.
Ecology and Pathogenesis
Habitat; symbiosis; biogeochemical significance; contributions to environment.
If relevant, how does this organism cause disease? Human, animal, plant hosts? Virulence factors, as well as patient symptoms.
References
Author
Page authored by _____, student of Prof. Jay Lennon at IndianaUniversity.
