Finegoldia magna

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Classification

Figure 1 Image of two distinct morphs of 'F. magna' [1]

Domain: Bacteria

Phylum: Firmicutes

Class: Clostridia

Order: Eubacteriales

Family: Peptoniphilaceae

Genus: Finegoldia

Species

Finegoldia magna [3]

NCBI: Taxonomy [4]

Description and Significance

Describe the appearance, habitat, etc. of the organism, and why you think it is important.

Genome Structure

Describe the size and content of the genome. How many chromosomes? Circular or linear? Other interesting features? What is known about its sequence?

Cell Structure, Metabolism and Life Cycle

Interesting features of cell structure; how it gains energy; what important molecules it produces.

Finegoldia magna has a cell structure that is a cocci, or spherical in shape and bacilli (rod-shaped bacteria). It has a cell size that varies from 0.8µm and 1.6µm in diameter, which occur predominantly in clusters but occasionally in short chains, as in Figure 2.

Figure 2 Electron microscopy images of F. magna strains ALB8 (top row) and 505 (bottom row). Bar represents 10 µm (left) and 5 µm (right). [2]

Ecology and Pathogenesis

Habitat; symbiosis; biogeochemical significance; contributions to environment.
If relevant, how does this organism cause disease? Human, animal, plant hosts? Virulence factors, as well as patient symptoms.

References

[1] Brüggemann, H., A. Jensen, S. Nazipi, H. Aslan, R. Meyer, A. Poehlein, E. Brzuszkiewics, M. Al-Zeer, V. Brinkmann, B. Söderquist. "Pan-genome analysis of the genus Finegoldia identifies two distinct clades, strain-specific heterogeneity, and putative virulence factors". Nature: Scientific Reports. 2018. 8:216.

[2] Murphy, E., Frick, I. "Gram-positive anaerobic cocci – commensals and opportunistic pathogens". FEMS Microbiology Reviews. 2013. 37:4. pp. 520-553.

[3] Murdoch, D.A., Gharbia, S.E., Rajendram, D. "Proposal to Restrict the Genus Peptostreptococcus (Kluyver & van Niel 1936) to Peptostreptococcus anaerobius". Anaerobe. 2000. 6:4. pp. 557-560.

[4] Schoch CL, et al. "NCBI Taxonomy: a comprehensive update on curation, resources and tools". Database (Oxford). 2020: baaa062. "PubMed: 32761142 PMC: PMC7408187".

Author

Page authored by Susan Reed, Nitesh Naren, Matt Millikin, students of Prof. Jay Lennon at Indiana University.