Group B Strep and Pregnancy: Difference between revisions

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<br>By Shawn Ruiz<br>
<br>By Shawn Ruiz<br>


<br>Group B Strep (GBS), also known as Streptococcus agalactiae, is a Gram-positive, beta-hemolytic, catalase-negative, facultative anaerobe that is a normal component of the gastrointestinal and genitourinary tracts<ref name=aa>[https://en.wikipedia.org/wiki/Streptococcus_agalactiae]</ref>. In fact, GBS colonizes the gastrointestinal and genitourinary tracts of up to 50% of healthy adults<ref name=bb>[https://pubmed.ncbi.nlm.nih.gov/17088932/]</ref>. Most healthy adults who are colonized by GBS will not experience any symptoms or GBS-related infections. While the bacteria is usually harmless in healthy adults, it is a major cause of meningitis, pneumonia, and and sepsis in neonates<ref name=cc>[https://evidencebasedbirth.com/groupbstrep/]</ref>. Moreover, GBS is the leading infectious cause of mortality in neonates in the United States; between four and six percent of babies who develop GBS disease die<ref name=dd>[https://www.ncbi.nlm.nih.gov/books/NBK482443/#:~:text=Preterm%20infants%20with%20early%2Donset,in%20term%20infants%5B2%5D.]</ref><ref name=ee>[https://www.cdc.gov/groupbstrep/about/fast-facts.html#references]</ref>. GBS causes both early onset (<7 days old) and late onset (7-90 days old) infections in neonates<ref name=dd/>. The main risk factor for an early-onset GBS infection in a neonate is colonization of a birthing person's genital tract with Group B strep during labor<ref name=dd/>.  
<br>Group B Strep (GBS), also known as Streptococcus agalactiae, is a Gram-positive, beta-hemolytic, catalase-negative, facultative anaerobe that is a normal component of the gastrointestinal and genitourinary tracts<ref name=aa>[https://en.wikipedia.org/wiki/Streptococcus_agalactiae]</ref>. In fact, GBS colonizes the gastrointestinal and genitourinary tracts of up to 50% of healthy adults<ref name=bb>[https://pubmed.ncbi.nlm.nih.gov/17088932/]</ref>. Most healthy adults who are colonized by GBS will not experience any symptoms or GBS-related infections. While the bacteria is usually harmless in healthy adults, it is a major cause of meningitis, pneumonia, and and sepsis in neonates<ref name=cc>[https://evidencebasedbirth.com/groupbstrep/]</ref>. Moreover, GBS is the leading infectious cause of neonatal mortality and morbidity in the United States; between four and six percent of babies who develop GBS disease die<ref name=dd>[https://www.ncbi.nlm.nih.gov/books/NBK482443/#:~:text=Preterm%20infants%20with%20early%2Donset,in%20term%20infants%5B2%5D.]</ref><ref name=ee>[https://www.cdc.gov/groupbstrep/about/fast-facts.html#references]</ref>. GBS causes both early onset (<7 days old) and late onset (7-90 days old) infections in neonates<ref name=dd/>. The main risk factor for an early-onset GBS infection in a neonate is colonization of a birthing person's genital tract with Group B strep during labor<ref name=dd/>.  




Revision as of 01:56, 15 March 2021

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Introduction

This artistic recreation, based on scanning electron microscopy (SEM), depicts a three-dimensional (3D), computer-generated image, of a group of Gram-positive, Streptococcus agalactiae (group B Streptococcus) bacteria. Photo Credit: Alissa Eckert, who is a medical illustrator at the CDC.


By Shawn Ruiz


Group B Strep (GBS), also known as Streptococcus agalactiae, is a Gram-positive, beta-hemolytic, catalase-negative, facultative anaerobe that is a normal component of the gastrointestinal and genitourinary tracts[1]. In fact, GBS colonizes the gastrointestinal and genitourinary tracts of up to 50% of healthy adults[2]. Most healthy adults who are colonized by GBS will not experience any symptoms or GBS-related infections. While the bacteria is usually harmless in healthy adults, it is a major cause of meningitis, pneumonia, and and sepsis in neonates[3]. Moreover, GBS is the leading infectious cause of neonatal mortality and morbidity in the United States; between four and six percent of babies who develop GBS disease die[4][5]. GBS causes both early onset (<7 days old) and late onset (7-90 days old) infections in neonates[4]. The main risk factor for an early-onset GBS infection in a neonate is colonization of a birthing person's genital tract with Group B strep during labor[4].




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Authored for BIOL 238 Microbiology, taught by Joan Slonczewski, 2021, Kenyon College.

  1. ↑ 1.0 1.1 [1]
  2. ↑ [2]
  3. ↑ [3]
  4. ↑ 4.0 4.1 4.2 [4]
  5. ↑ [5]
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