Hepatitis B Virus X gene in Hepatocellular Carcinoma

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A Viral Biorealm page on the family Hepatitis B Virus X gene in Hepatocellular Carcinoma

miRNAs are short, endogenous RNA molecules of 19- to 24- nucleotides in length that are expressed widely in eukaryotes that [1]. The main function of a miRNA is to bind its complementary (target) mRNA sequence and inhibit translation, a process known as RNA silencing. Since plants, fungi, and animals have evolved RNA silencing as an innate antiviral mechanism, it is not surprising that an infecting virus can induce changes in cellular miRNA or synthesize viral miRNA the antiviral activities of its host [2]. A common goal of many hepatitis B virus (HBV) researchers is to identify the roles of host miRNAs in replication an pathogenesis of the virus. Furthermore, particular interactions between host miRNAs and HBV have been correlated with instance and _____ of hepatocellular carcinoma.

Figure 1. Transmission electron micrograph of Ebola virus. [1].

First subtopic

hep b infection, HCC

Hepatitis B Virus Protein x in Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is among the most frequently diagnosed cancers worldwide. For over forty years physicians and researchers have observed an association between HBV infection and development of HCC.