Human Chromosomal Integration of Latent State Human Herpes Virus 6 (HHV-6): Difference between revisions
From MicrobeWiki, the student-edited microbiology resource
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==Pathophysiology of HHV-6 Infection== | ==Pathophysiology of HHV-6 Infection== | ||
[[Image:Rash.jpg|thumb|400px|right| [http://andbabybmakesthree.wordpress.com/2009/11/11/wordless-wednesday-roseola/ Figure 4.] HHV-6 infection results in roseola, often diagnosed by a characteristic red rash. The roseola rash can form as either raised bumps or can be flat. It is non-contagious and is usually found on the neck, abdomen, back, and trunk, but can also be present on the arms and legs]] | |||
===Initial Infection=== | ===Initial Infection=== | ||
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===Latency in Healthy Children and Adults=== | ===Latency in Healthy Children and Adults=== | ||
===Reactivation in Immunosuppressed Individuals=== | ===Reactivation in Immunosuppressed Individuals=== | ||
==HHV-6 and Associated Disease States== | ==HHV-6 and Associated Disease States== | ||
Revision as of 20:13, 1 November 2010
By: Kerri-Lynn Conrad
Introduction
Figure 1. Transmission electron micrograph visualization of Human Herpes Virus-6 (HHV-6) on the surface of a human lymphocyte. HHV-6 is the causative agent of roseola, a disease that effects nearly every human infant.
Genomic Structure of HHV-6
Figure 2. Genomic organization of HHV-6B. The asterisk indicates the start of lytic genomic replication. Viral telomeric sequences are indicated by green bars T1 and T2. Open arrows represent protein coding regions.
HHV-6 Replication Cycle
Figure 3. Lytic replication cycle of HHV-6.
Epidemiology
Pathophysiology of HHV-6 Infection
Figure 4. HHV-6 infection results in roseola, often diagnosed by a characteristic red rash. The roseola rash can form as either raised bumps or can be flat. It is non-contagious and is usually found on the neck, abdomen, back, and trunk, but can also be present on the arms and legs
Initial Infection
Latency in Healthy Children and Adults
Reactivation in Immunosuppressed Individuals
HHV-6 and Associated Disease States
Latency through Human Chromosomal Integration
Transmission through Germ Line
Future Work
References
Edited by Kerri-Lynn Conrad, student of Joan Slonczewski for BIOL 375 Virology, 2010, Kenyon College.
