Human Chromosomal Integration of Latent State Human Herpes Virus 6 (HHV-6)

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By: Kerri-Lynn Conrad

Introduction

Figure 1. Transmission electron micrograph visualization of Human Herpes Virus-6 (HHV-6) on the surface of a human lymphocyte. HHV-6 is the causative agent of roseola, a disease that effects nearly every human infant.


Genomic Structure of HHV-6

HHV-6 Replication Cycle

Epidemiology

Pathophysiology of HHV-6 Infection

Initial Infection

Latency in Healthy Children and Adults

Reactivation in Immunosuppressed Individuals

HHV-6 Associated Disease States

Latency through Human Chromosomal Integration

Transmission through Germ Line

Future Work

References

Edited by Kerri-Lynn Conrad, student of Joan Slonczewski for BIOL 375 Virology, 2010, Kenyon College.