Mouth
This template is a general guideline of how to design your site. You are not restricted to this format, so feel free to make changes to the headings and subheadings and to add additional sections as appropriate.
Description of Niche
Where located?
Physical Conditions?
What are the conditions in your niche? Temperature, pressure, pH, moisture, etc.
Influence by Adjacent Communities (if any)
Is your niche close to another niche or influenced by another community of organisms?
Conditions under which the environment changes
Do any of the physical conditions change? Are there chemicals, other organisms, nutrients, etc. that might change the community of your niche.
Who lives there?
Which microbes are present?
You may refer to organisms by genus or by genus and species, depending upon how detailed the your information might be. If there is already a microbewiki page describing that organism, make a link to it.
Are there any other non-microbes present?
Plants? Animals? Fungi? etc.
Do the microbes that are present interact with each other?
Describe any negative (competition) or positive (symbiosis) behavior
Do the microbes change their environment?
Do they alter pH, attach to surfaces, secrete anything, etc. etc.
Do the microbes carry out any metabolism that affects their environment?
Do they ferment sugars to produce acid, break down large molecules, fix nitrogen, etc. etc.
Correlation between periodontitis and coronary heart disease
Several theories exist to explain the relationship between coronary heart disease and periodontitis. One such theory includes the role of fibrinogen in linking the two. Fibrinogen is a plasma glycoprotein synthesized in the liver. After coagulation, it is converted in Fibrin, the protein involved in blood clots. The study took 95 subjects and separated them into a healthy control group, moderately and severely chronic periodontitis group, coronary heart disease group, and moderately and severely chronic periodontitis coexisting with coronary heart disease group. After measuring routinely diagnosis procedure for both periodontitis and cardiovascular heart disease along with levels of fibrinogen, results showed fibrinogen levels in subjects with MSP and MSP+CHD to be much higher than those of the healthy controlled group. It was concluded that people with periodontitis may be more at risk for developing cardiac heart disease when taking into consideration fibrinogen as the biological basis.
Bacterial markers of periodontal diseases
Among the various bacteria present in the subgingival deposit, three have been the center of study due to their prevalence in periodontal disease. First, the Tannerella forsythensis, an anaerobic Gram-negative known to possess pathogenic potential. Second, the Actinobacillus actinomycetemcomitans with the ability to attach itself to the enamel surface after the consumption of sugar to produce an acid resulting in the erosion of the enamel surface. And the third, the Porphyronmonas gingivalis, a gram negative bacteria with a virulence factor allowing it to invade the gum tissue. They measure the bacteria on 495 subjects aged 6-82 with the use of the 16S ribosomal RNA based polymerase chain reaction (PCR). Their studies showed an increase in the amount of T. forsythensis and P. gingivalis on older subjects when compared to the adolescents. Furthermore, an increase in T. forsythensis was also seen within the tobacco smokers or the subjects. It was finally concluded that the T. forsythensia had a correlation between periodontal disease in tobacco smoking and elder individuals.
References
Edited by [Mason Chen, Diana Kirchmann, Alvin Kwong, Lydi Martinez, Mei Ng, Gabriel Tran, Kristen Watanabe, Kathryn Yee], students of Rachel Larsen
