Telaprevir (VX-950) a novel antiviral treatment for Hepatitis C virus patients: Difference between revisions

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==Introduction==
The hepatitis C virus (HCV) epidemic continues to be a serious health threat, infecting over 170 million people worldwide (Lin <i>et al.</i> 2005). Moreover, three to four million people are newly infected each year (Ressink <i>et al.</i> 2006). The infection is often asymptomatic in its early stages, but the majority of HCV-infected individuals develop chronic hepatitis over time, which eventually advances to liver scarring (cirrhosis), and liver cancer (hepatocellular carcinoma) (Moriishi and Matsuura 2007). The epidemiology of the virus is not well understood. However, it is known that HCV is transmissible through sexual contact and blood-to-blood contact. In the United States, blood-to-blood transmission of HCV is greatest among injecting drug users (IDUs). Although the virus can be acquired through blood transfusions, and contact with other sources of infected blood product (Simmonds 2000).

Revision as of 01:12, 2 November 2010

Introduction

The hepatitis C virus (HCV) epidemic continues to be a serious health threat, infecting over 170 million people worldwide (Lin et al. 2005). Moreover, three to four million people are newly infected each year (Ressink et al. 2006). The infection is often asymptomatic in its early stages, but the majority of HCV-infected individuals develop chronic hepatitis over time, which eventually advances to liver scarring (cirrhosis), and liver cancer (hepatocellular carcinoma) (Moriishi and Matsuura 2007). The epidemiology of the virus is not well understood. However, it is known that HCV is transmissible through sexual contact and blood-to-blood contact. In the United States, blood-to-blood transmission of HCV is greatest among injecting drug users (IDUs). Although the virus can be acquired through blood transfusions, and contact with other sources of infected blood product (Simmonds 2000).

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