Name
Bench ID
Date
MICR3004
Classification
Higher order taxa
Bacteria – Bacteroidetes – Bacteroidia – Bacteroidales – Porphyromonadaceae - Porphyromonas - P. gingivalis
Species
Species: Porphyromonas gingivalis
Strain: W88
Description and significance
Genome structure
The genome of strain W88 is comprised of a circular chromosome made up of 2 343 479 bp’s. On average the guanine and cytosine content make up approximately 48.3 % of the genome. The circular chromosome encodes 1909 protein genes 65 RNA genes. 4 ribosomal operons (rrn, 5S rRNA-23S rRNA-tRNAAla-tRNAIle-16S rRNA) including 53 tRNA genes showing specificity for all 20 amino acids have been documented. Interestingly the number of rrn operons and tRNA genes in strain W83 were identical to those of an avirulent strain counterpart ATCC 33277. Nonetheless the extensive rearrangement between the two strains through the introduction of mobile elements inevitably altered the virulence of the bacterium.
The genome of W83 is composed predominately (85%) of ORF. Encoding a total of 1,990 ORF, 1075 presented detectable biological roles. Of the remaining ORF, 184 were categorised as a conserved hypothetical protein or conserved domain protein, 208 had to known function, and 523 encoded hypothetical proteins.
Cell structure and metabolism
Ecology
Pathology
Application to biotechnology
Bioengineering, biotechnologically relevant enzyme/compound production, drug targets,…
Current research
Summarise some of the most recent discoveries regarding this species.
References
NOT YET LINKED TO TEXT
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This page is written by Amy Pham for the MICR3004 course, Semester 2, 2016