Talk:Gastritis and Peptic Ulcer Disease Caused by Helicobacter pylori

Overall this is a great page that does a good job at explaining Helicobacter as it is relevant to human disease. The introduction has all the information that it needs already in it, but you may be able to draw in more readers by slightly changing the order in which the facts are presented. It might be interesting to start off with the diseases caused by Helicobacter and how many people carry the bacterium but show no symptoms. You could then go on to talk about some of the features of Helicobacter (size, Gram-negative, microaerophilic) and how these features enhance the bacterium's ability to function as a pathogen. I found the research section a little hard to follow at times—explaining some of the experimental techniques, like what the antibody names stand for and how the antibody scheme works (what exactly each type of antibody binds to) as well as why the cagD and cagE, and virD4 genes were used as gene markers instead of other genes might help readers when reading this section. It was interesting to read about the advantages and disadvantages of each of the diagnostic tests. For the treatment section, how do doctors know when treatment is successful in patients with ulcers (how do they verify that the ulcer has healed and won't reappear)? I enjoyed the prevention section and the specific food references you used. Also, be sure to cite the figures and pictures that you borrowed from other sources. Nice work!

I liked the page a lot and thought you covered a lot of the relevant information about H. pylori. One thing that I wondered about was whether the bacteria exist in the "wild" at all, or whether they are only found in humans. Are they only pathogens? I thought that there was a lot of depth early on, especially in the pathogenesis section, and I was wondering whether you might go into a little more explanation in the treatment section with the mechanisms by which these things work. I thought that the diagnostic section and the prevention section were both very readable and a little bit less molecular, which I thought was a nice contrast. With a little editing and proofreading (there were some grammatical and spelling errors throughout), this can be a really great paper! Well done.